Research Assistant I — : Biologics Res (19-00505) – MA – Framingham

The Research Assistant will work in a small team setting to support developability assays for protein therapeutics including monospecific and multispecific antibodies. You will be involved with analytical methods for routine testing and extended characterization of physicochemical attributes of therapeutic proteins.
You will be responsible for analysis of protein purity by SDS-PAGE, HPLC-SEC, HIC and DLS.
You will conduct protein stability assays, by thermal denaturation and accelerated degradation methods.
You will analyze, interpret, document and present data to the team.
You will contribute to group knowledge and expertise through collaboration and idea exchange with a multidisciplinary team.
The individual must be highly motivated, ready to learn new skills and adapt, have meticulous bench-work and record-keeping, and be able to function independently.

Experience with standard protein characterization techniques such as SDS-PAGE, HPLC (SEC, HIC) and/or CE-based (CE-SDS, icIEF) methods.
Experience with routine lab equipment and methods, including preparing buffers, measuring pH, UV absorbances, etc.
A strong understanding of protein structure and biophysical chemistry.
Demonstrated ability to analyze, interpret and present data in a clear manner.
Excellent communication and interpersonal skills.

BA/BS or MS degree in Biochemistry, Biophysics, or a related field with 1-3 years of research experience in protein engineering, protein biochemistry or biophysics is required.
Source: Job Diva – Job Listing

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